Continuous renal replacement therapy combined with fomepizole is effective in the clearance of ethylene glycol: a case report
نویسندگان
چکیده
Ethylene glycol toxicity can be fatal without prompt treatment. Treatment options may include ethanol, fomepizole, and intermittent hemodialysis (IHD). IHD is usually preferred; however, depending ...
منابع مشابه
A Case of Ethylene Glycol intoxication with Acute Renal Injury: Successful Recovery by Fomepizole and Renal Replacement Therapy
Ethylene glycol is a widely used and readily available substance. Ethylene glycol ingestion does not cause direct toxicity; however, its metabolites are highly toxic and can be fatal even in trace amounts. Poisoning is best diagnosed through inquiry, but as an impaired state of consciousness is observed in most cases, poisoning must be suspected when a significantly elevated osmolar gap or high...
متن کاملFomepizole for ethylene glycol and methanol poisoning.
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متن کاملThe Role of Hemodialysis and Fomepizole in Ethylene Glycol Intoxication
Ethylene glycol is one of the most common toxic alcohol ingestions requiring hemodialysis for treatment. With the FDA approval in 1997 of fomepizole (4-methylpyrazole), the indications for hemodialysis in addition to fomepizole for ethylene glycol poisoning have been examined in recent articles and case reports. Fomepizole, a competitive inhibitor of alcohol dehydrogenase, binds to the same sit...
متن کاملRole of fomepizole in the management of ethylene glycol toxicity.
OBJECTIVE To systematically review English-language articles on fomepizole administration in patients with ethylene glycol poisoning. DATA SOURCES MEDLINE, EMBASE, Current Contents, and PubMed. Search terms were fomepizole, 4-methylpyrazole, and ethylene glycol. The search was supplemented with a bibliographic review of all relevant articles. STUDY SELECTION All published reports of fomepiz...
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ژورنال
عنوان ژورنال: Toxicology communications
سال: 2021
ISSN: ['2473-4306']
DOI: https://doi.org/10.1080/24734306.2021.1973818